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Antibiotics and Steroids at the Same Time? "The Boob" [HM] 2 kids; Kingman, Arizona 15719 posts
4th Feb '12

Okay, I'm sure I've seen or heard of this before. Basically my son is always really sick, long story. Anyways, they prescribed him 3 days of predisone and also a zithromax prescription.



So, steroids basically take your immune system down, and antibiotics don't work right without your immune system so how are the antibiotics supposed to work if you are on a steroid at the same time? Idk I was just thinking about it and can't figure out if he is being put at a disadvantage by taking both at the same time.



Thoughts? If you are a medical professional and could better explain it to me, by all means LOL.

No longer here at BG California 3488 posts
4th Feb '12
Quoting "The b**b" [HM]:" Okay, I'm sure I've seen or heard of this before. Basically my son is always really sick, long story. ... [snip!] ... taking both at the same time. Thoughts? If you are a medical professional and could better explain it to me, by all means LOL."


What is he sick with?

Squeaky McGee 2 kids; 3 angel babies; Indiana 65151 posts
4th Feb '12

Does he have pneumonia? Yes, the steroids will suppress the immune system, but their main function is to reduce inflammation. The steroids will open up the airway and the antibiotics will treat the infection. They don't really counteract each other.

No longer here at BG California 3488 posts
4th Feb '12
Quoting Squeaky McGee:" Does he have pneumonia? Yes, the steroids will suppress the immune system, but their main function is ... [snip!] ... The steroids will open up the airway and the antibiotics will treat the infection. They don't really counteract each other."


:!::!: This is what I was just thinking.

"The Boob" [HM] 2 kids; Kingman, Arizona 15719 posts
4th Feb '12
Quoting Squeaky McGee:" Does he have pneumonia? Yes, the steroids will suppress the immune system, but their main function is ... [snip!] ... The steroids will open up the airway and the antibiotics will treat the infection. They don't really counteract each other."


He doesn't have penumonia this time. He had it a couple months back. Basically he has an ear infection that hasn't gone away for months and there are upper respiratory complications with it. (croupy cough, congestion, stuffy/runny nose, goopy eyes, etc).



ETA: His breathing got so bad he was having retractions. But no pneumonia, no rsv, no flu, etc.

I'm me 4 kids; Kentucky 3109 posts
4th Feb '12

Predisone helps to reduce inflamation and is often given with antibiotics especially if there is a stubborn respiratory infection. The antibiotic is given to get rid of the infection and the predisone to reduce the inflammation.

"The Boob" [HM] 2 kids; Kingman, Arizona 15719 posts
4th Feb '12
IQuoting I'm me:" Predisone helps to reduce inflamation and is often given with antibiotics especially if there is a stubborn ... [snip!] ... respiratory infection. The antibiotic is given to get rid of the infection and the predisone to reduce the inflammation."


I totally get their purposes, I just know that the way the steroid works is by reducing the immune system's response. That's what brings down the inflammation.

I'm me 4 kids; Kentucky 3109 posts
4th Feb '12
Quoting "The b**b" [HM]:" I totally get their purposes, I just know that the way the steroid works is by reducing the immune system's response. That's what brings down the inflammation."


If you want to get technical it is a beta blocking corticosteroid that decreases/prevents the release of substances in the body that cause inflammation. And it only causes suppression of the immune system if it is taken for extended time periods.

Squeaky McGee 2 kids; 3 angel babies; Indiana 65151 posts
5th Feb '12
Quoting I'm me:" If you want to get technical it is a beta blocking corticosteroid that decreases/prevents the release ... [snip!] ... the body that cause inflammation. And it only causes suppression of the immune system if it is taken for extended time periods."


It suppresses the immune system in general.

I'm me 4 kids; Kentucky 3109 posts
6th Feb '12

The part of the immunosupression that it does involves the migration of polymorphonuclear leukocytes, fibroblast, reversal to increase capillary permeability, and lysosomal stabilization, minimal mineralcorticoid activity. It is made to suppress a certain aspect of the immune system and not the whole thing. It only causes unwanted suppression of the immune system if taken for extened time periods. Predisone is given to treat severe inflammation, immunosupersion, neoplasms, MS, collagen disorders, dermatological disorders.