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.................................... KyliesMommy2012 Tokyo, Japan 1159 posts
26th May '13

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user banned 3 kids; Portland, Michigan 15675 posts
26th May '13

I don't remember when I started to notice that it was working for me but others around me noticed changes after two weeks.

Chelsie Nichnadowicz Cranford, New Jersey 130 posts
26th May '13

<blockquote><b>Quoting KyliesMommy2012:</b>" I got put on 50mg of zoloft about a week ago now. My doctor said it'd take AT LEAST 3 weeks to kick in. When did YOU start noticing it kicking in?"</blockquote>



I was on it for 11 years, can honestly say it will take two weeks maybe even three to kick in. It has to be in your system for a while.

user banned Due April 2; Georgia 7200 posts
26th May '13

I was prescribed it adter I had the boys, and my OB said it'd take at least 2 weeks to kick in. I took the ones the nurses gave me in the hospital, but I didn't like how it made me feel. I never got my prescription filled

*Brittnee* 4 kids; 1 angel baby; Utah 4011 posts
26th May '13

about two weeks

Snow 1 child; Storybrooke, ME, United States 34017 posts
26th May '13

I took it years ago. It was awful :(

DifferentDay Due June 2; 34 kids; Tennessee 3473 posts
26th May '13

2wks. Hubby noticed the changes. And boy oh boy when I go off it for a wk at a time (forget/lazy to take it) u can tell the difference.

Proginoskes II 3 kids; North Carolina 1295 posts
27th May '13

I started feeling slightly better within a week. It took about 2 weeks for it to fully kick in.
I take 25mg Zoloft and 300mg Wellbutrin.