Studies conducted on animals have shown that the utilization of Naproxen during pregnancy can lead to decreased fetal body weight, an increase in the occurrence of fetal abnormalities and an increase in embryofetal death.
However, although there is no controlled data in human pregnancies to make use of, experts believe that
it's best for pregnant women to avoid using Naproxen. This is because its usage in late pregnancy can cause premature closure of the ductus arteriosus and prolong labor and delivery. The only time when Naproxen is allowed during pregnancy is when there are no alternatives and benefit outweighs risk.